Active substance: Ciprofloxacin
As it appears that no one has really taken any interest in working on this it appears that the responsability has fallin on my shoulders. As such any help from the other editors would be geatly appreciated. I am fairly new here at wikipedia so I am still a "newbie" when it comes to such editing.
But I am far from being a "newbie" when it comes to these drugs as I have been researching and writing articles concerning these issues for well over a decade now.
The reference material I have accumulated over the years fills 4 four drawer file cabinets and several hard drives, and was referenced within the petitions filed by Public Citizen as well as the Attorney General of the State of Illinois.
Either here or on my talk page.
This would be greatly appreciated. What is the mechanism by which these drugs lead to tendon damage? Here is the lawsuit. She was a student, but the pain is so great that she does not have the strength to carry her text books.
The cipro was given for "food poisoning" a disorder that rarely requires any drug treatment.
My research since she became ill indicates that tendon damage to the point of tendon rupture is not "rare" but much more common than Bayer would have you believe.
For the few patients so affected, cipro is the drug from hell. The FDA has required strong warnings on the labels and inserts warning of severe side effcts, that are so severe that people have committed suicide to stop the pain.
The research of fluorquinolone drugs such as cipro shows that many drugs in this class were so toxic and produced such severe side effects that many have been taken off the market. There are a number of websites that have documented in layman's words these horrible side effects, which those writers have taken from original peer reviewed medical journals.
This list goes on and on and on and on and on. The physician has no clue as to what these drugs can and will do to a patient.
The physician will likely prescribe steriods and other drugs which often have adverse interactions with the fluoroquinone drugs, sometimes resulting in unexpect outcomes such as death.
There is no known treatment for a majority of the severe reactions.
Such reactions often DO NOT abate once therapy is discontinued in a subset of those so treated and the current research indicates that such events are to be considered permanent in nature.
Perhaps the wide range of actions and side effects is due to the ability of flourine in Cipro to substitute for hydrogen due to their very similar van der Waals radiuses.
Consequently, people should not use cipro or any of the fluoroquinone class of antibiotics without consideration of the risk of permanent adverse health as an outcome posibility. Physicians should prescribe these drugs only in cases of life threatening disease and then only as a third line of treatment after other drugs have failed.
The patient must be informed that these side effects are not rare and that they can be life long in duration.
The websites you cite above are, unfortunately, not reliable sources.